Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines.
Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines.
F. Paris,P. Balaguer,5 Authors,C. Sultan
2002 · DOI: 10.1016/S0303-7207(02)00094-1
Molecular and Cellular Endocrinology · 211 Citations
TLDR
Evidence is provided that several phenyl derivatives present both estrogenic and antiandrogenic activity and these environmental chemicals may have a negative impact on androgen action during fetal and post-natal life.