PK 11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent.
PK 11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent.
D. Zisterer,Cristina Sun̈ol,2 Authors,E. Rodríguez-Farré
1995 · DOI: 10.1016/0024-3205(95)02230-G
Life Science · 10 Citations
TLDR
The effect of pretreatment with PK 11195 elicited a protective effect against the convulsant activity of orally administered lindane, which reduced the frequency of animals exhibiting convulsions and delayed the time to onset of these seizures.