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Open‐label topical application of tetrahexyldecyl ascorbate and acetyl zingerone containing serum improves the appearance of photoaging and uneven pigmentation

Mildred Min,S. H. Pérez Damonte,Raja K. Sivamani

2024 · DOI: 10.1111/jocd.16315
Journal of Cosmetic Dermatology · 1 Citations

TLDR

Tetrahexyldecyl ascorbate and acetyl zingerone are potent antioxidants that have been shown to have anti‐photoaging and anti‐pigmentation effects and no studies have assessed how they may synergistically act on the skin.

Abstract

Skin photoaging and uneven pigmentation are common dermatological concerns. Tetrahexyldecyl ascorbate (THDA) and acetyl zingerone (AZ) are potent antioxidants that have been shown to have anti‐photoaging and anti‐pigmentation effects. THDA is a more stable and penetrable form of vitamin C. AZ is an antioxidant derived from ginger which has clinical evidence for improving photoaging. However, no studies have assessed how they may synergistically act on the skin.