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On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection.

J. Molina,C. Capitant,33 Authors,J. Delfraissy

2015 · DOI: 10.1056/NEJMoa1506273
New England Journal of Medicine · 1,410 Citations

TLDR

The use of TDF-FTC before and after sexual activity provided protection against HIV-1 infection in men who have sex with men, and the treatment was associated with increased rates of gastrointestinal and renal adverse events.