Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract
Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract
Koichi S. Kobayashi,M. Chamaillard,4 Authors,R. Flavell
2005 · DOI: 10.1126/SCIENCE.1104911
Science · 1,904 Citations
TLDR
It is shown that protective immunity mediated by Nod2 recognition of bacterial muramyl dipeptide is abolished in Nod1-deficient mice, providing a possible mechanism for Nod 2 mutations in CD.