Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1G93A ALS mice and after partial muscle denervation
Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1G93A ALS mice and after partial muscle denervation
R. Mancuso,Anna Martinez-Muriana,11 저자,X. Navarro
2016 · DOI: 10.1016/j.nbd.2016.07.023
Neurobiology of Disease · 47회 인용
TLDR
It is demonstrated that Nrg1-I plays a crucial role in the collateral reinnervation process, opening a new window for developing novel ALS therapies for functional recovery rather than preservation.