Nesfatin-1 evokes Ca2+ signaling in isolated vagal afferent neurons via Ca2+ influx through N-type channels.
Nesfatin-1 evokes Ca2+ signaling in isolated vagal afferent neurons via Ca2+ influx through N-type channels.
Yusaku Iwasaki,H. Nakabayashi,3 Authors,T. Yada
2009 · DOI: 10.1016/j.bbrc.2009.10.085
Biochemical and Biophysical Research Communications - BBRC · 75 Citations
TLDR
Results provide direct evidence that nesfatin-1 activates vagal afferent neurons by stimulating Ca(2+) influx through N-type channels, demonstrating the machinery through which peripheral nesFatin- 1 can convey signals to the brain.