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NR1I3 inhibits colorectal cancer growth by enhancing PCK1-mediated gluconeogenesis.

Huanying Shi,Zi-Qian Wu,11 Authors,Qunyi Li

2025 · DOI: 10.1016/j.cbi.2025.111734
Chemico-Biological Interactions · 0 Citations

TLDR

It is suggested that NR1I3 inhibits CRC by converting glycolysis to gluconeogenesis via PCK1, suggesting potential indicators and treatment targets for CRC progression.