NEK9-mediated Wnt signalling repressor TLE3 rewires Docetaxel resistance in cancer cells by inducing pyroptosis.
S. Ansari,Sibasish Mohanty,8 Authors,Rupesh Dash
2025 · DOI: 10.1038/s41416-025-03148-5
British Journal of Cancer · 0 Citations
TLDR
It is demonstrated that NEK9 plays an important role in Docetaxel resistance and the novel combination of NEK9 inhibitor Fostamatinib and Docetaxel needs further clinical investigation in advanced OSCC.
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