Mycobacterial Infection in TLR2 and TLR6 Knockout Mice
Mycobacterial Infection in TLR2 and TLR6 Knockout Mice
I. Sugawara,Hiroyuki Yamada,3 Authors,S. Akira
2003 · DOI: 10.1111/j.1348-0421.2003.tb03404.x
Microbiology and immunology · 209 Citations
TLDR
TLR2 does not play an essential role in the pathogenesis of murine tuberculosis, although it is important for defense against mycobacterial infection, and TLR6 was not different from WT mice in terms of pulmonary histopathology, mRNA expression and CFU assay.