Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection.
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection.
M. van der Sluis,B. D. de Koning,8 Authors,A. Einerhand
2006 · DOI: 10.1053/J.GASTRO.2006.04.020
Gastroenterology · 1,605 Citations
TLDR
This study shows that Muc2 deficiency leads to inflammation of the colon and contributes to the onset and perpetuation of experimental colitis.