Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
N. Serbina,E. Pamer
2006 · DOI: 10.1038/ni1309
Nature Immunology · 1,738 Citations
TLDR
In blood, Ccr2−/− monocytes could traffic to sites of infection, demonstrating that CCR2 is not required for migration from the circulation into tissues, and determining the frequency of Ly6Chi monocytes in the circulation.