Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense.
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense.
Naoko Satoh-Takayama,C. Vosshenrich,9 Authors,J. D. Di Santo
2008 · DOI: 10.1016/j.immuni.2008.11.001
Immunity · 1,122 Citations
TLDR
RORgammat-driven diversification of intestinal NKp46+ cells thereby specifies an innate cellular defense mechanism that operates at mucosal surfaces.