MicroRNA‐130a controls bone marrow mesenchymal stem cell differentiation towards the osteoblastic and adipogenic fate
MicroRNA‐130a controls bone marrow mesenchymal stem cell differentiation towards the osteoblastic and adipogenic fate
Zhang-Yuan Lin,Hongbo He,Min Wang,Jieyu Liang
2019 · DOI: 10.1111/cpr.12688
Cell Proliferation · 162 Citations
TLDR
The role of miRNAs in regulating BMSC differentiation swift fate in age‐related osteoporosis is explored.
Abstract
With age, bone marrow mesenchymal stem cells (BMSC) have reduced ability of differentiating into osteoblasts but have increased ability of differentiating into adipocytes which leads to age‐related bone loss. MicroRNAs (miRNAs) play major roles in regulating BMSC differentiation. This paper explored the role of miRNAs in regulating BMSC differentiation swift fate in age‐related osteoporosis.