Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate‐exposed human islets
Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate‐exposed human islets
Quan Wen,Azazul Chowdhury,4 Authors,Peter Bergsten
2023 · DOI: 10.1111/dom.15270
Diabetes, obesity and metabolism · 6 Citations
Abstract
To elucidate how proinsulin synthesis and insulin was affected by metformin under conditions of nutrient overstimulation.