Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
Wanling Yang,Huayang Tang,74 Authors,Y. Lau
2013 · DOI: 10.1016/j.ajhg.2012.11.018
American Journal of Human Genetics · 206 Citations
TLDR
Genetic variants in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B are identified as associated with SLE and point to potential roles of cell-cycle regulation, autophagy, and DNA demethylation in SLE pathogenesis.