Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor
Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor
Karishma Kailass,O. Sadovski,4 Authors,Andrew A. Beharry
2019 · DOI: 10.1039/c9sc00283a
Chemical Science · 26 Citations
TLDR
A ratiometric fluorescent chemosensor that selectively measures human carboxylesterase 2 activity with application in pancreatic cancer patient-derived xenografts is reported.
Abstract
We report the development of a ratiometric fluorescent chemosensor that selectively measures human carboxylesterase 2 (hCES2) activity with application in pancreatic cancer patient-derived xenografts.