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Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

P. Nelson,D. Dickson,32 Authors,J. Schneider

2019 · DOI: 10.1093/brain/awz099
1,311 Citations

TLDR

A recently recognized brain disorder that mimics the clinical features of Alzheimer’s disease: Limbic-predominant Age-related TDP-43 Encephalopathy (LATE).

Abstract

Nelson et al. describe a recently recognized brain disorder that mimics the clinical features of Alzheimer’s disease: Limbic-predominant Age-related TDP-43 Encephalopathy (LATE). They review the literature and present consensus-based recommendations of an international, multidisciplinary working group, providing guidelines for diagnosis and staging of LATE neuropathological changes.