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Kinetics and Dynamics of Intravenous Adinazolam, N‐Desmethyl Adinazolam, and Alprazolam in Healthy Volunteers

K. Venkatakrishnan,Kerry E. Culm,4 Authors,D. Greenblatt

2005 · DOI: 10.1177/0091270004269105
Journal of clinical pharmacology · 35 Citations

TLDR

Results indicate that the benzodiazepine‐like effects occurring after adinazolam administration are mediated by mainly NDMAD, and the relation of both alprazolam and N DMAD plasma concentrations to DSST performance could be described by a modified exponential model.