KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron
Hélène Louis-dit-Picard,J. Barc,35 Authors,X. Jeunemaître
2012 · DOI: 10.1038/ng.2218
Nature Genetics · 280 Citations
TLDR
A role is established for KLHL3 as a new member of the complex signaling pathway regulating ion homeostasis in the distal nephron and indirectly blood pressure.