Interferon Regulatory Factor-Two Restricts Expression of Interferon-Stimulated Genes to the Endometrial Stroma and Glandular Epithelium of the Ovine Uterus1

These results suggest that IRF-2 in the LE and sGE restricts IFNτ induction of ISGs to the S and GE, which likely involves formation and actions of the transcription factors ISGF3 and, perhaps, IRf-1.