Interference with endogenous EZH2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression
Interference with endogenous EZH2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression
L. Cai,Zehua Wang,Denghua Liu
2016 · DOI: 10.1007/s13277-015-4416-9
Tumor Biology · 26 Citations
TLDR
In vivo tumorigenicity experiments results demonstrated that interference with endogenous EZH2 by shRNA specific to EzH2 or inhibition EZh2 by DZNep could significantly increase antitumor effects in nude mice.