Innate immune recognition of infected apoptotic cells directs TH17 cell differentiation
Innate immune recognition of infected apoptotic cells directs TH17 cell differentiation
M. Torchinsky,Johan Garaude,Andrea P. Martin,J. Blander
2009 · DOI: 10.1038/nature07781
Nature · 377 Citations
TLDR
The results demonstrate that infected apoptotic cells are a critical component of the innate immune signals instructing TH17 differentiation, and point to pathogens particularly adept at triggering apoptosis that might preferentially induce TH17-mediated immunity.