Inhibitory effects of 7-epiclusianone on glucan synthesis, acidogenicity and biofilm formation by Streptococcus mutans.
Inhibitory effects of 7-epiclusianone on glucan synthesis, acidogenicity and biofilm formation by Streptococcus mutans.
R. Murata,Luciana Salles Branco de Almeida,4 Authors,H. Koo
2008 · DOI: 10.1111/j.1574-6968.2008.01117.x
FEMS Microbiology Letters · 41 Citations
TLDR
The data show that 7-epiclusianone disrupts the extracellular and intracellular sugar metabolism of S. mutans, and holds promise as a novel, naturally occurring compound to prevent biofilm-related oral diseases.