Immunogenicity and In Vitro and In Vivo Protective Effects of Antibodies Targeting a Recombinant Form of the Streptococcus mutans P1 Surface Protein
Immunogenicity and In Vitro and In Vivo Protective Effects of Antibodies Targeting a Recombinant Form of the Streptococcus mutans P1 Surface Protein
M. T. Batista,Renata D. Souza,6 Authors,R. C. Ferreira
2014 · DOI: 10.1128/IAI.02074-14
Infection and Immunity · 16 Citations
TLDR
The utility of P139–512 as a potential candidate for the development of anticaries vaccines and as a tool for functional studies of S. mutans P1 is confirmed, as it preserves relevant conformational epitopes as well as salivary agglutinin (SAG)-binding activity.