Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.
Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.
T. Takayama,N. Kamada,10 Authors,T. Hibi
2010 · DOI: 10.1053/j.gastro.2010.05.040
Gastroenterology · 194 Citations
TLDR
The balance of NKp44(+)/NKp46(+) NK cells is disrupted in intestinal mucosa of patients with CD and these cells might mediate the pathogenesis of CD by producing IFN-gamma.