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Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Minjia Tan,Hao Luo,15 Authors,Yingming Zhao

2011 · DOI: 10.1016/j.cell.2011.08.008
Cell · 1,673 Citations

TLDR

The identification of 67 previously undescribed histone modifications is reported, increasing the current number of known histone marks by about 70%, and lysine crotonylation (Kcr) is investigated, confirming that it represents an evolutionarily-conserved histone posttranslational modification.