IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens1
IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens1
Sara M. Dann,M. Spehlmann,5 Authors,L. Eckmann
2008 · DOI: 10.4049/jimmunol.180.10.6816
Journal of Immunology · 184 Citations
TLDR
IL-6 is an important regulator of host defense against C. rodentium by protecting the mucosa against ulcerations which can act as a microbial niche for the bacteria.