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IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.

S. Brand,F. Beigel,14 Authors,J. Dambacher

2006 · DOI: 10.1152/AJPGI.00513.2005
573 Citations

TLDR

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and IEC migration, which suggests an important function in intestinal inflammation and wound healing.