IL-17 and Th17 Cells.
IL-17 and Th17 Cells.
T. Korn,E. Bettelli,M. Oukka,V. Kuchroo
2009 · DOI: 10.1146/annurev.immunol.021908.132710
Annual Review of Immunology · 5,050 Citations
TLDR
The investigation of the differentiation, effector function, and regulation of Th17 cells has opened up a new framework for understanding T cell differentiation and now appreciate the importance of Th 17 cells in clearing pathogens during host defense reactions and in inducing tissue inflammation in autoimmune disease.
