Hypoglycemia-associated autonomic failure in healthy humans: comparison of two vs three periods of hypoglycemia on hypoglycemia-induced counterregulatory and symptom response 5 days later.
Hypoglycemia-associated autonomic failure in healthy humans: comparison of two vs three periods of hypoglycemia on hypoglycemia-induced counterregulatory and symptom response 5 days later.
A. Moheet,Anjali F. Kumar,3 Authors,E. Seaquist
2014 · DOI: 10.1210/jc.2013-3493
Journal of Clinical Endocrinology and Metabolism · 27 Citations
TLDR
It is demonstrated that exposure of healthy humans to three 2-hour hypoglycemic episodes over 30 hours leads to significant blunting in counterregulatory and symptom response to subsequent hypoglycemia on day 5.