Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection.
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection.
Rong Liu,W. Paxton,7 Authors,N. Landau
1996 · DOI: 10.1016/S0092-8674(00)80110-5
Cell · 3,247 Citations
TLDR
A CKR-5 allele present in the human population appears to protect homozygous individuals from sexual transmission of HIV-1 and is suggested to provide a means of preventing or slowing disease progression.