Heart Dose Is an Independent Dosimetric Predictor of Overall Survival in Locally Advanced Non–Small Cell Lung Cancer
Heart Dose Is an Independent Dosimetric Predictor of Overall Survival in Locally Advanced Non–Small Cell Lung Cancer
C. Speirs,T. DeWees,7 Authors,C. Robinson
2017 · DOI: 10.1016/j.jtho.2016.09.134
Journal of Thoracic Oncology · 254 Citations
TLDR
Heart dose is associated with OS and cardiac toxicity for patients with LA NSCLC treated with chemoradiotherapy, and factors independently associated with worse OS were increasing heart V50, heart volume, lung V5, and bilateral mediastinal lymph node involvement.