HSD11B1, HSD11B2, PTGS2, and NR3C1 Expression in the Peri-Implantation Ovine Uterus: Effects of Pregnancy, Progesterone, and Interferon Tau1
HSD11B1, HSD11B2, PTGS2, and NR3C1 Expression in the Peri-Implantation Ovine Uterus: Effects of Pregnancy, Progesterone, and Interferon Tau1
R. M. Simmons,M. Satterfield,2 Authors,T. E. Spencer
2010 · DOI: 10.1095/biolreprod.109.079608
Biology of Reproduction · 79 Citations
TLDR
Hypotheses that endometrial epithelial HSD11B1 expression is induced by P4 as well as stimulated by IFNT and PTGS2-derived prostaglandins and that HSD 11B1-regenerated cortisol acts via NR3C1 to regulate ovineendometrial functions during early pregnancy are supported.