Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
A. Franke,D. McGovern,93 Authors,M. Parkes
2010 · DOI: 10.1038/ng.717
Nature Genetics · 2,676 Citations
TLDR
A meta-analysis of six Crohn's disease genome-wide association studies and a series of in silico analyses highlighted particular genes within these loci implicated functionally interesting candidate genes including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2 and TAGAP.