Generation and characterization of human iPSC lines (FAHZJUi001-A and FAHZJUi002-A) from two familial recurrent hydatidiform mole patients carrying homozygous mutation in the NLRP7 gene
Generation and characterization of human iPSC lines (FAHZJUi001-A and FAHZJUi002-A) from two familial recurrent hydatidiform mole patients carrying homozygous mutation in the NLRP7 gene
Limeng Cai,Jiayang Wan,6 Authors,Jianhua Qian
2026 · DOI: 10.1007/s13577-025-01346-0
Human Cell · 0 Citations
TLDR
The generation and characterization of iPSC lines from FRHM patients harboring homozygous NLRP7 variants offer a unique platform to dissect molecular pathways driving NLRP7-mediated reproductive failure, overcoming long-standing barriers in FRHM pathogenesis research.