G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions
G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions
C. Esnault,Talha Magat,12 Authors,J. Andrau
2023 · DOI: 10.1038/s41588-023-01437-4
Nature Genetics · 46 Citations
TLDR
G4access is a nuclease-based method for identifying DNA G-quadruplex forming regions genome-wide in open chromatin using sequencing and observes that G4access peaks are unmethylated, while methylation at pG4s correlates with nucleosome repositioning on DNA.