FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis
FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis
Serkan Kir,S. Beddow,7 Authors,D. Mangelsdorf
2011 · DOI: 10.1126/science.1198363
Science · 586 Citations
TLDR
FGF19 treatment restored the loss of glycogen in diabetic animals lacking insulin and activates a physiologically important, insulin-independent endocrine pathway that regulates hepatic protein and glycogen metabolism.