Explainable hierarchical machine-learning approaches for multimodal prediction of conversion from mild cognitive impairment to Alzheimer’s disease
Explainable hierarchical machine-learning approaches for multimodal prediction of conversion from mild cognitive impairment to Alzheimer’s disease
Soheil Zarei,Mohsen Saffar,2 Authors,A. Shalbaf
2025 · DOI: 10.1007/s13246-025-01618-x
Physical and Engineering Sciences in Medicine · 3 Citations
TLDR
An advanced machine learning framework that integrates hierarchical feature selection with multiple classifiers to predict progression from mild cognitive impairment to Alzheimer’s disease is developed, transforming the model from a predictive black box into a clinically actionable tool for early diagnosis and patient stratification.