Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics.
Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics.
K. Subbarao,Hualan Chen,8 Authors,Y. Matsuoka
2003 · DOI: 10.1006/VIRO.2002.1742
Virology · 271 Citations
TLDR
This is the first successful attempt to develop an H5N1 vaccine seed virus resembling those used in currently licensed influenza A vaccines with properties that make it a promising candidate for further evaluation in humans.