Ethanol Reduces GABAA α1 Subunit Receptor Surface Expression by a Protein Kinase Cγ-Dependent Mechanism in Cultured Cerebral Cortical Neurons
Ethanol Reduces GABAA α1 Subunit Receptor Surface Expression by a Protein Kinase Cγ-Dependent Mechanism in Cultured Cerebral Cortical Neurons
Sandeep Kumar,A. Suryanarayanan,4 Authors,A. Morrow
2010 · DOI: 10.1124/mol.109.063016
Molecular Pharmacology · 48 Citations
TLDR
It is suggested that ethanol exposure selectively alters PKCγ translocation to GABAA receptors andPKCγ regulates G ABAA α1 receptor trafficking after ethanol exposure.