Essential moieties of myricetins, quercetins and catechins for binding and inhibitory activity against α-Glucosidase.
Essential moieties of myricetins, quercetins and catechins for binding and inhibitory activity against α-Glucosidase.
M. Fu,Wenxia Shen,4 Authors,Lijun Sun
2021 · DOI: 10.1016/j.bioorg.2021.105235
59 Citations
TLDR
It was found that C4 = O, C2 = C3, 3-OH and 5'-OH were essential moieties for α-glucosidase inhibition of myricetin that was shown with the highest inhibitory activity and that the methods above can be combined reasonably to characterize flavonoid-enzyme binding interactions.