Enantiopure Sulfinyl Aniline as a Removable and Recyclable Chiral Auxiliary for Asymmetric C(sp3 )-H Bond Activation.
Enantiopure Sulfinyl Aniline as a Removable and Recyclable Chiral Auxiliary for Asymmetric C(sp3 )-H Bond Activation.
Soufyan Jerhaoui,Faouzi Chahdoura,3 Authors,F. Colobert
2016 · DOI: 10.1002/chem.201603507
Chemistry · 40 Citations
TLDR
An original and recyclable chiral bidentate aniline-sulfoxide-based directing group has been developed and an unprecedented palladacycle intermediate generated through C-H activation of the cyclopropane moiety has been isolated and fully characterized.