Ectopic expression of human angiopoietin-1 promotes functional recovery and neurogenesis after focal cerebral ischemia
Ectopic expression of human angiopoietin-1 promotes functional recovery and neurogenesis after focal cerebral ischemia
Z. Meng,Mengtao Li,4 Authors,Yun Bai
2014 · DOI: 10.1016/j.neuroscience.2014.02.036
Neuroscience · 33 Citations
TLDR
Results demonstrated that lentivirus-mediated Ang1 gene transfer led to improved neurological behavior and reduced infarction volume, and protected against blood-brain barrier leakage in the ischemic rats, suggesting that Ang1 is a promising agent for the treatment of cerebral ischemia.