Discovery of Intratumoral Oncolytic Bacteria Toward Targeted Anticancer Theranostics (Adv. Sci. 20/2023)
Yamato Goto,Seigo Iwata,Mikako Miyahara,Eijiro Miyako
2023 · DOI: 10.1002/advs.202370131
Advancement of science · 0 Citations
TLDR
The microbial consortium AUN composed of Proteus mirabilis (A‐gyo) and Rhodopseudomonas palustris (UN‐gya) can trigger the immune system to eliminate cancer cells, provoking strong anticancer responses in various mouse models of cancer.
Abstract
Oncolytic Bacteria In article number 2301679, Eijiro Miyako and co‐workers discover the microbial consortium AUN composed of Proteus mirabilis (A‐gyo) and Rhodopseudomonas palustris (UN‐gyo) from solid tumors. The AUN can trigger the immune system to eliminate cancer cells, provoking strong anticancer responses in various mouse models of cancer. The AUN has promising potential for innovative cancer theranostics.
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