Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.
H. Ishigame,S. Kakuta,11 Authors,Y. Iwakura
2009 · DOI: 10.1016/j.immuni.2008.11.009
Immunity · 1,081 Citations
TLDR
It is demonstrated with Il17a(-/-), Il17f(-/-) mice that IL-17F played only marginal roles, if at all, in the development of delayed-type and contact hypersensitivities, autoimmune encephalomyelitis, collagen-induced arthritis, and arthritis in Il1rn(-/-).