Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
O. Takeuchi,K. Hoshino,5 Authors,S. Akira
1999 · DOI: 10.1016/S1074-7613(00)80119-3
Immunity · 3,652 Citations
TLDR
It is demonstrated that TLR2 and TLR4 recognize different bacterial cell wall components in vivo andTLR2 plays a major role in Gram-positive bacterial recognition.