Differential Effects of the Dual Orexin Receptor Antagonist Almorexant and the GABAA-α1 Receptor Modulator Zolpidem, Alone or Combined with Ethanol, on Motor Performance in the Rat
Differential Effects of the Dual Orexin Receptor Antagonist Almorexant and the GABAA-α1 Receptor Modulator Zolpidem, Alone or Combined with Ethanol, on Motor Performance in the Rat
M. Steiner,H. Lecourt,2 Authors,F. Jenck
2011 · DOI: 10.1038/npp.2010.224
Neuropsychopharmacology · 51 Citations
TLDR
Almorexant is less likely to show strong sedation, excessive myorelaxation, or interaction with alcohol than commonly prescribed hypnotics such as zolpidem and can be immediately reversed to full alertness like under physiological sleep.