Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells.
Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells.
R. Mebius,P. Rennert,I. Weissman
1997 · DOI: 10.1016/S1074-7613(00)80371-4
Immunity · 723 Citations
TLDR
It is proposed that the novel subset of CD4+CD3-LTbeta+ fetal cells is instrumental in the development of lymphoid tissue architecture.