Delivery of expression constructs of secreted frizzled-related protein 4 and its domains by chitosan–dextran sulfate nanoparticles enhances their expression and anti-cancer effects
Delivery of expression constructs of secreted frizzled-related protein 4 and its domains by chitosan–dextran sulfate nanoparticles enhances their expression and anti-cancer effects
Vanathi Perumal,F. Arfuso,2 Authors,A. Dharmarajan
2018 · DOI: 10.1007/s11010-017-3225-4
Molecular and Cellular Biochemistry · 9 Citations
TLDR
Both the SFRP4 and NLD nanoparticles significantly reduced the viability of MM cells, with the NLD showing the greatest effect and the CS–DS nanoparticle effects were observed at an earlier time point and with lower DNA concentrations.